Lymphofollicular hyperplasia is an increase in the size of the pocket of cells found in lymph node. These follicles contain normal white blood cells called lymphocytes. Your body produces more lymphocytes to help prevent bacteria, viruses, and other types of germs from entering the bloodstream.
Lymphadenopathy; Lymphofollicular hypertrophy
Armitage JO, Bierman PJ. Approach to the patient with lymphadenopathy and splenomegaly. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 168.
Review Date 9/27/2017
Updated by: Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.