Skip navigation

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

URL of this page: https://medlineplus.gov/druginfo/meds/a688006.html

Lovastatin

pronounced as (loe' va sta tin)

Why is this medication prescribed?

Lovastatin is used together with diet, weight-loss, and exercise to reduce the risk of heart attack and stroke and to decrease the chance that heart surgery will be needed in people who have heart disease or who are at risk of developing heart disease. Lovastatin is also used to decrease the amount of cholesterol (a fat-like substance) and other fatty substances in the blood. Lovastatin may also be used to decrease the amount of cholesterol and other fatty substances in the blood in adults and children and teenagers 10 to 17 years of age who have familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally). Lovastatin is in a class of medications called HMG CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body.

Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats with lovastatin may help prevent heart disease, angina (chest pain), strokes, and heart attacks.

How should this medicine be used?

Lovastatin comes as a tablet and an extended-release (long-acting) tablet to take by mouth. The regular tablet usually is taken once or twice a day with meals. The extended-release tablet usually is taken once a day at bedtime. Take lovastatin at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take lovastatin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the extended-release tablets whole; do not split, chew, or crush them.

Your doctor may start you on a low dose of lovastatin and gradually increase your dose, not more than once every 4 weeks.

Continue to take lovastatin even if you feel well. Do not stop taking lovastatin without talking to your doctor.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking lovastatin,

  • tell your doctor and pharmacist if you are allergic to lovastatin, any other medications, or any of the ingredients in lovastatin tablets or extended-release tablets. Ask your pharmacist for a list of the ingredients.
  • Some medications should not be taken with lovastatin. Other medications may cause dosing changes or extra monitoring when taken with lovastatin. Make sure you have discussed any medications you are currently taking or plan to take before starting lovastatin with your doctor and pharmacist. Before starting, stopping, or changing any medications while taking lovastatin, please get the advice of your doctor or pharmacist.
  • tell your doctor if you have or ever had liver disease. Your doctor will order laboratory tests to see how well your liver is working even if you do not think you have liver disease. Your doctor will probably tell you not to take lovastatin if you have liver disease or if the tests show that you may be developing liver disease.
  • tell your doctor if you drink more than two alcoholic beverages daily, if you are 65 years of age or older, or if you have or have ever had seizures, muscle aches or weakness, low blood pressure, diabetes, or thyroid or kidney disease.
  • tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while taking lovastatin, call your doctor. Lovastatin may harm the fetus.
  • tell your doctor if you are breastfeeding or plan to breastfeed. You should not breastfeed while you are taking this medication.
  • do not breastfeed while you are taking this medication.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking lovastatin. If you are hospitalized due to serious injury or infection, tell the doctor who treats you that you are taking lovastatin.
  • ask your doctor about the safe use of alcoholic beverages while you are taking lovastatin. Alcohol can increase the risk of serious side effects.

What special dietary instructions should I follow?

Eat a low-fat, low-cholesterol diet. Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. You can also visit the National Cholesterol Education Program (NCEP) website for additional dietary information at https://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Avoid drinking grapefruit juice while taking lovastatin.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Lovastatin may cause side effects. Tell your doctor if these symptoms are severe or do not go away:

  • constipation
  • memory loss or forgetfulness
  • confusion
  • headache

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately or get emergency medical help:

  • muscle pain, tenderness, or weakness
  • lack of energy
  • weakness
  • fever
  • dark colored urine
  • yellowing of the skin or eyes
  • pain in the upper right part of the stomach
  • extreme tiredness
  • nausea
  • unusual bleeding or bruising
  • loss of appetite
  • flu-like symptoms
  • rash
  • hives
  • itching
  • difficulty breathing or swallowing
  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • hoarseness

Lovastatin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (https://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. https://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (https://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of emergency/overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor may order laboratory tests during your treatment, especially if you develop symptoms of liver damage.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking lovastatin.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names

  • Altocor®
  • Altoprev®
  • Mevacor®

This branded product is no longer on the market. Generic alternatives may be available.

Last Revised - 08/20/2024