Isoxsuprine

Isoxsuprine is used to relieve the symptoms of central and peripheral vascular diseases such as arteriosclerosis, Buerger's disease, and Raynaud's disease.

Isoxsuprine comes as a tablet to take by mouth. It is usually taken three or four times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take isoxsuprine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Isoxsuprine is also used occasionally to treat menstrual pain or prevent premature labor. Talk to your doctor about the possible risks of using this drug for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking isoxsuprine,

• tell your doctor and pharmacist if you are allergic to isoxsuprine, any other medications, or any of the ingredients in isoxsuprine tablets. Ask your doctor or pharmacist for a list of the ingredients.
• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking isoxsuprine, call your doctor.
• talk to your doctor about the risks and benefits of taking isoxsuprine if you are 65 years of age or older. Older adults should not usually take isoxsuprine because it is not as safe and effective as other medications that can be used to treat the same condition.
• if you are having surgery, including dental surgery, tell your doctor or dentist that you are taking isoxsuprine.
• you should know that this medication may make you drowsy or dizzy. Do not drive a car or operate machinery until you know how isoxsuprine will affect you. Avoid sudden changes in posture and get up slowly when lying down.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Isoxsuprine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• weakness
• dizziness
• flushing (feeling of warmth)
• upset stomach
• vomiting
• stomach pain

Some side effects may be serious. If you experience any of the following symptoms, call your doctor immediately:

• rash
• fast heartbeat
• chest pain

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (https://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Isoxsuprine may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach. https://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (https://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

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