Insulin icodec-abae Injection

Insulin icodec-abae injection is used to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Insulin icodec-abae injection is a long-acting form of insulin. It works by replacing the insulin that is normally produced by the body and by helping move sugar from the blood into other body tissues where it is used for energy. It also stops the liver from producing more sugar.

Insulin icodec-abae injection comes as a solution (liquid) to inject subcutaneously (under the skin). Inject insulin icodec-abae once weekly. Use insulin icodec-abae injection on the same day each week.

Use insulin icodec-abae injection exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Never use insulin icodec-abae injection when you have symptoms of hypoglycemia (low blood sugar) or if you have checked your blood sugar, and it is low.

Insulin icodec-abae controls diabetes but does not cure it. Continue to use insulin icodec-abae injection even if you feel well. Do not stop using insulin icodec-abae injection without talking to your doctor. Do not switch to another brand or type of insulin or change the dose of any type of insulin you are using without talking to your doctor. Always check the insulin label to make sure you received the right type of insulin from the pharmacy.

Before you use insulin icodec-abae injection yourself the first time, read the instructions for use that comes with the medication. Ask your doctor or pharmacist to show you how to inject it. Ask your doctor or pharmacist if you have any questions about injecting insulin icodec-abae.

Insulin icodec-abae comes as pens for injection, be sure to read and understand the manufacturer's instructions. If you are blind or have poor eyesight, do not use this pen without help.

Never reuse needles and never share pens. Always remove the needle from the pen right after you inject your dose. Discard needles and syringes in a puncture-resistant container. Ask your doctor or pharmacist how to dispose of the puncture-resistant container

Inject insulin icodec-abae in your thighs, stomach area, or upper arms. Use a different site for each injection. Do not inject where the skin is thick, pitted, lumpy, tender, bruised, scaly, hard, or into areas of skin where there are scars or skin is damaged.

Always look at your insulin icodec-abae before you inject it. Insulin icodec-abae solution should be clear and colorless. Do not use this type of insulin icodec-abae if it is colored, cloudy, thickened, or contains solid particles. Do not use icodec-abae insulin after the expiration date printed on the pen has passed.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before using insulin icodec-abae injection,

• tell your doctor or pharmacist if you are allergic to this medication, any part of this medication, or any other medications, foods or substances. Tell your doctor or pharmacist about the allergy and what symptoms you had.
• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take while using insulin icodec-abae injection. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
• tell your doctor if you have low blood sugar. Your doctor will probably tell you not to use insulin icodec-abae injection.
• tell your doctor if you have vision problems, or have or have ever had heart failure, or heart, liver, or kidney disease.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Insulin icodec-abae injection, call your doctor.
• ask your doctor what to do if you get sick, experience unusual stress, or change your diet, exercise, or activity schedule. These changes can affect your dosing schedule and the amount of insulin you will need.
• ask your doctor how often you should check your blood sugar. Be aware that hypoglycemia may affect your ability to perform tasks such as driving and ask your doctor if you need to check your blood sugar before driving or operating machinery.
• if you are having surgery, including dental surgery, tell the doctor or dentist that you are using Insulin icodec-abae injection.
• alcohol may cause a change in blood sugar. Ask your doctor about the safe use of alcoholic beverages while you are using insulin icodec-abae injection.

It is important to eat a healthful diet, and to eat about the same amounts of the same kinds of food at about the same times each day. Skipping or delaying meals or changing the amount or kind of food you eat can cause problems with your blood sugar control. Unless your doctor tells you otherwise, continue your normal diet.

If a dose is missed, give a dose of insulin icodec-abae as soon as possible within 4 days. Then resume your once weekly dosing schedule, one week from the day the missed dose was used. If more than 4 days have passed, skip the missed dose and give the next dose on the next scheduled day. Increase your blood glucose monitoring if you miss a dose of insulin icodec-abae.

Insulin icodec-abae injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• pain, bruising, swelling, or redness at the site of injection
• skin thickening or pits at the injection site

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

• rash, itching; shortness of breath; wheezing; or swelling of the face, tongue, or throat
• dizziness, drowsiness, confusion, blurred vision, fast heartbeat, or sweating
• shortness of breath, large weight gain in a short period of time, or swelling of the arms, hands, lower legs, or feet
• weakness, tiredness, cramps, constipation, irregular heartbeat

Insulin icodec-abae injection may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (https://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in and out of reach of children. Store it in the refrigerator. Do not freeze or keep next to the refrigerator cooling element. Do not use insulin icodec-abae injection if it has been frozen.

Unopened insulin icodec-abae injection may be stored at room temperature for up to 12 weeks or until the expiration date on the package if refrigerated. Insulin icodec-abae injection that is in use (opened), may be kept refrigerated or at room temperature for up to 12 weeks. The total amount of time at room temperature may not exceed 12 weeks for unopened or in-use time.

Keep all medication out of sight and reach of children as many containers are not child-resistant. Always lock safety caps. Place the medication in a safe location – one that is up and away and out of their sight and reach. https://www.upandaway.org

Dispose of unneeded medications in a way so that pets, children, and other people cannot take them. Do not flush this medication down the toilet. Use a medicine take-back program. Talk to your pharmacist about take-back programs in your community. Visit the FDA's Safe Disposal of Medicines website https://goo.gl/c4Rm4p for more information.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

• loss of consciousness
• seizure

Keep all appointments with your doctor and the laboratory. Your blood sugar and glycosylated hemoglobin (HbA1c) should be checked regularly to determine your response to insulin icodec-abae. Your doctor will also tell you how to check your response to this medication by measuring your blood sugar levels at home. Follow these instructions carefully.

You should always wear a diabetic identification bracelet to be sure you get proper treatment in an emergency.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.

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