Typhoid Vi Polysaccharide Vaccine

Typhoid Vi polysaccharide vaccine may prevent typhoid fever that may occur with infection due to the Salmonella typhi bacteria, usually occurring after eating food or drinking water that is contaminated with the bacteria. Typhoid fever is found in most areas of Central and South America, the African continent, the Near East and the Middle East, Southeast Asia and the Indian subcontinent.

Infection with Salmonella typhi can cause the following: fever, headache, weakness, and gastrointestinal (GI) symptoms (stomach pain, constipation, diarrhea, loss of appetite).

Typhoid Vi polysaccharide vaccine does not contain live bacteria. It works by triggering the body to make antibodies against the bacteria to provide a defense against potential infection.

Typhoid Vi polysaccharide vaccine comes as a solution (liquid) to be given intramuscularly (into a muscle) by a healthcare provider.

Typhoid Vi polysaccharide vaccine is given as a single dose. A booster dose may be given every 2 years if you continue to be exposed to Salmonella typhi.

Tell your vaccine provider if you:

• have had an allergic reaction to this vaccine, any part of this vaccine, any other vaccine or any drug, food or substance. Tell your vaccine provider about the allergy and what symptoms you had.
• have a fever, are immunosuppressed due to a medical condition, or if you are taking an immunosupressant medication.
• tell your vaccine provider if you are pregnant or breast feeding.

In some cases, your health care provider may decide to postpone vaccination to a future visit.

Side effects that have been reported with typhoid polysaccharide vaccine include:

• pain, redness, tenderness, or hardness at the site of injection
• nausea, diarrhea, vomiting
• fever
• muscle aches

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

• rash, hives, difficulty breathing or swallowing

People sometimes faint after medical procedures, including vaccination. Tell your provider if you feel dizzy or have vision changes or ringing in the ears.

Adverse reactions should be reported to the Vaccine Adverse Event Reporting System (VAERS). Your health care provider will usually file this report, or you can do it yourself. Visit https://vaers.hhs.gov or call 1-800-822-7967. VAERS is only for reporting reactions, and VAERS staff members do not give medical advice.

• Read the Vaccine Information Sheet (VIS) that your vaccine provider will give you or you can obtain it at https://www.cdc.gov/vaccines/hcp/current-vis/index.html
• Ask your healthcare provider.
• Call your local or state health department.

• Typhim Vi^®