Carbachol and Brimonidine Ophthalmic

Carbachol and brimonidine ophthalmic is used to treat presbyopia (gradual loss of eyes' ability to focus on close object). Carbachol is in a class of medications called cholinergic agents. It works by making your pupils (black center of the eye) constrict (get smaller) that makes it easier to focus up close. Brimonidine is in a class of medications called alpha-adrenergic agonists. It works by keeping your pupils from dilating (getting too large).

Carbachol and brimonidine ophthalmic comes as a solution (liquid) to be placed in the eye. Use once daily. Use carbachol and brimonidine at around the same time every day.

Use carbachol and brimonidine ophthalmic exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Your doctor will have you get an eye exam before starting to use this medication.

Remove contact lens prior to using carbachol and brimonidine ophthalmic and do not place them back in eye until 10 minutes after using the eye drops.

Do not use any other eye drops within 5 minutes of using carbachol and brimonidine ophthalmic.

Avoid letting the tip of the vial come in contact with your eye, eyelids, or any other surface.

Each vial is for single use. Once opened and used, throw away the vial.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before using carbachol and brimonidine ophthalmic,

• tell your doctor or pharmacist if you are allergic to this medication, any part of this medication, or any other medications, foods or substances. Tell your doctor or pharmacist about the allergy and what symptoms you had.
• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
• tell your doctor if you have or have ever had depression, iritis (inflammation of the iris of the eye), eye disease of the retina, orthostatic hypotension (sudden fall in blood pressure that occurs when a person assumes a standing position) , or vascular (veins and arteries) diseases, including Raynaud’s disease.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using carbachol and brimonidine ophthalmic, call your doctor.
• you should know that carbachol and brimonidine ophthalmic may cause temporary blurred, dark or dim vision. Do not drive a car or operate machinery until vision returns to normal. Use caution with night driving.

Unless your doctor tells you otherwise, continue your normal diet.

Use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.

Carbachol and brimonidine ophthalmic may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• headache
• eye irritation or pain

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

• sudden onset of flashing lights, floaters or vision loss

Carbachol and brimonidine ophthalmic may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (https://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the foil pouch it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture (not in the bathroom).

Keep all medication out of sight and reach of children as many containers are not child-resistant. Always lock safety caps. Place the medication in a safe location – one that is up and away and out of their sight and reach. https://www.upandaway.org

Dispose of unneeded medications in a way so that pets, children, and other people cannot take them. Do not flush this medication down the toilet. Use a medicine take-back program. Talk to your pharmacist about take-back programs in your community. Visit the FDA's Safe Disposal of Medicines website https://goo.gl/c4Rm4p for more information.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

• sweating
• abdominal cramps, diarrhea, nausea
• low heart rate, dizziness, lightheadedness

Keep all appointments with your doctor and eye doctor.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.

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