Depemokimab-ulaa Injection

Depemokimab-ulaa injection is used to treat severe asthma. Depemokimab-ulaa is in a class of medications called monoclonal antibodies. It works by reducing a certain type of white blood cell that causes inflammation in airways.

Depemokimab-ulaa comes as a solution (liquid) to be injected subcutaneously (just under the skin) by a healthcare provider into the front of your thighs, upper arm, or stomach. It is injected once every 6 months.

Depemokimab-ulaa injection is not used to treat a sudden attack of asthma symptoms. Talk to your doctor about how to treat symptoms of a sudden asthma attack. If your asthma symptoms get worse or if you have asthma attacks more often, talk to your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before receiving depemokimab-ulaa injection,

• tell your doctor or pharmacist if you are allergic to this medication, any part of this medication, or any other medications, foods or substances. Tell your doctor or pharmacist about the allergy and what symptoms you had.
• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
• tell your doctor if you have or have ever had a parasitic (worm) infection.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while receiving depemokimab-ulaa injection, call your doctor.

Unless your doctor tells you otherwise, continue your normal diet.

If you miss an appointment to receive a dose of depemokimab-ulaa injection, call your doctor to reschedule the appointment.

Depemokimab-ulaa injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• redness, itching, or swelling at the injection site
• sneezing; runny, stuffy, or itchy nose
• sore throat or flu-like symptoms
• joint pain

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

• rash; hives; difficulty breathing; swelling of the eyes, face, lips, tongue, or throat; or fainting, dizziness, or feeling lightheaded

Depemokimab-ulaa injection may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (https://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor.

Ask your pharmacist any questions you have about depemokimab-ulaa injection.

Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.

• Exdensur^®