Etripamil nasal spray

Etripamil nasal spray is used to treat episodes of paroxysmal supraventricual tachycardia (PSVT; sudden episodes of very fast heart rate). Etripamil nasal spray is in a class of medications called calcium channel blockers. It works by interrupting the abnormal pulse in the heart that causes PSVT allowing the heart to return to normal sinus rhythm.

Etripamil nasal spray comes as a solution in device to spray in the nose. Each device contains two sprays. At the start of PSVT symptoms, use one spray into each nostril. If symptoms persist after 10 minutes, use the second device that comes with each prescription. If symptoms do not improve within 20 minutes of the second dose, call your doctor or seek emergency medical care. Do not use more than 2 devices in a 24 hour period (maximum of 4 sprays).

If you do not give the first full dose or the device malfunctions, do not use or give the second dose for at least 10 minutes.

You or a caregiver will be shown how to use the medicine before your first dose. You will also be given the instructions for use. Read these carefully.Talk to your doctor or pharmacist if you have any questions on how to use the medicine.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before using ertipamil nasal spray,

• tell your doctor or pharmacist if you are allergic to this medication, any part of this medication, or any other medications, foods or substances. Tell your doctor or pharmacist about the allergy and what symptoms you had.
• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
• tell your doctor if you have heart failure or any other heart condition. Your doctor may tell you not to use ertipamil nasal spray depending on what the heart condition is or how severe it is.
• tell your doctor if you are pregnant or plan to become pregnant. If you discover you are pregnant after having used ertipamil nasal spray, call your doctor.
• tell your doctor if you are breastfeeding. If you must use ertipamil nasal spray while breastfeeding, stop breastfeeding and discard pumped milk for 12 hours after the dose.
• you should know that ertipamil nasal spray may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. Use ertipamil nasal spray in a sitting position and a safe place with low risk of falling. If you experience dizziness, lightheadedness, weakness, nausea, sweaty, seeing spots or tunnel vision, or loss of consciousness after using etripamil nasal spray, your caregiver or who is around you should place you on your back and seek medical help.

Unless your doctor tells you otherwise, continue your normal diet.

Etripamil nasal spray may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• stuffy or runny nose
• nose or throat discomfort or irritation
• nose bleed

Etripamil nasal spray may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (https://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). The nasal spray device is intended for one time use and should be discarded after use.

Keep all medication out of sight and reach of children as many containers are not child-resistant. Always lock safety caps. Place the medication in a safe location – one that is up and away and out of their sight and reach. https://www.upandaway.org

Dispose of unneeded medications in a way so that pets, children, and other people cannot take them. Do not flush this medication down the toilet. Use a medicine take-back program. Talk to your pharmacist about take-back programs in your community. Visit the FDA's Safe Disposal of Medicines website https://goo.gl/c4Rm4p for more information.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.

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