Riboflavin 5'-phosphate ophthalmic

Riboflavin 5'-phosphate ophthalmic is used as part of a corneal cross-linking procedure (an eye procedure that uses UV light) to treat keratoconus (an eye condition in which the cornea thins and changes shape causing blurred vision and other vision changes). Riboflavin 5'-phosphate is a type of vitamin B. It works as a photoenhancer that is activated by UV light to help form bonds to strengthen the cornea.

Riboflavin 5'-phosphate comes as a solution (liquid) to be instilled in the eye by a doctor. It is given in a doctor's office or healthcare facility with UV light as part of a corneal cross-linking procedure.

Before you receive riboflavin 5'-phosphate eye drops, your doctor will numb your eye to reduce discomfort during the procedure. Your doctor will also have you wear a special pair of goggles to wear over your eyes during the procedure. Ask your doctor if you have any questions about the procedure.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before receiving riboflavin 5'-phosphate eye drops,

• tell your doctor or pharmacist if you are allergic to this medication, any part of this medication, or any other medications, foods or substances. Tell your doctor or pharmacist about the allergy and what symptoms you had.
• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
• tell your doctor if you have had cataract surgery or any other corneal problems. Your doctor may tell you not to receive riboflavin 5'-phosphate eye drops.
• tell your doctor if you have or have ever had an infection in your eye or any other eye problem.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding.
• you should know that riboflavin 5'-phosphate eye drops may make your eyes more sensitive to light. Plan to wear sunglasses after the procedure to help with any light sensitivity.

Unless your doctor tells you otherwise, continue your normal diet.

Riboflavin 5'-phosphate eye drops may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• eye redness or irritation
• eye pain
• blurred vision
• teary eyes
• eyelid swelling

Some side effect can be serious. If you experience any of these symptoms, call your doctor immediately:

• sudden decrease in vision

Riboflavin 5'-phosphate eye drops may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (https://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor.

Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.

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• Epioxa^® HD