Bupivacaine Liposomal Injection

Bupivacaine liposomal injection comes as a suspension (liquid) to be injected by a healthcare provider. It is usually given at the time of surgery, either just before or at the end of the procedure.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before receiving bupivacaine liposomal,

• tell your doctor or pharmacist if you are allergic to this drug, any part of this drug, or any other drugs, foods or substances. Tell your doctor or pharmacist about the allergy and what symptoms you had.
• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
• tell your doctor if you have or have ever had glucose-6- phosphate dehydrogenase deficiency (an inherited disease that affects red blood cells); methemoglobinemia (a condition that affect how the red blood cells work to carry oxygen); or lung, liver, heart or blood vessel disease.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding.
• if you are having another surgery within 96 hours, including dental surgery, tell the doctor or dentist that you recently received bupivacaine liposomal injection.

Unless your doctor tells you otherwise, continue your normal diet.

Bupivacaine liposomal may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• nausea, vomiting, constipation

Some side effects can be serious. If you experience any of these symptoms and call your doctor immediately or get emergency medical treatment:

• itching, redness, hives, swelling of the tongue and/or throat, difficulty breathing, fast heartbeat, fainting, excessive sweating, or fever
• restlessness, anxiety, incoherent speech, lightheadedness, numbness and tingling of the mouth and lips, metallic taste, ringing in the ears, dizziness, blurred vision, tremors, twitching, depression, drowsiness, or seizures
• pale, gray, or blue colored skin; headache; rapid heart rate; shortness of breath; lightheadedness; or fatigue

Bupivacine liposomal may cause a temporary loss of feeling or ability to move a part of your body that may last up to 5 days. Talk to your doctor about the risks of taking this medication.

Bupivacine liposomal may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (https://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep all appointments with your doctor.

Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.