Inclisiran injection

Inclisiran injection comes as a solution (liquid) to be given subcutaneously (under the skin) into abdomen, upper am, or thigh. It is usually given once and then repeated again in 3 months and then every 6 months after that. Inclisiran injection is given by a doctor or nurse at a doctor's office or clinic.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking inclisiran,

• tell your doctor and pharmacist if you are allergic to inclisiran, any other medications, or any of the ingredients in inclisiran injection. Ask your pharmacist for a list of the ingredients.
• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking inclisiran injection, call your doctor.

Unless your doctor tells you otherwise, continue your normal diet.

If a scheduled administration is missed by less than 3 months, inclisiran injection should be given as soon as possible and continued on the regular schedule. If a scheduled administration is missed by more than 3 months, inclisiran injection dosing schedule should be restarted by giving a dose now and then another in 3 months and then every 6 months thereafter.

Inclisiran injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• pain, swelling, redness at injection site
• joint pain
• pain or burning on urination
• loose or frequent stools
• cough, shortness of breath, wheezing, low fever or chest tightness
• pain in arms or legs
• difficulty breathing

Inclisiran injection may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (https://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to inclisiran.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.