URL of this page: https://medlineplus.gov/druginfo/meds/a621033.html

Aducanumab-avwa Injection

pronounced as (a" due kan' ue mab)

Why is this medication prescribed?

Aducanumab-avwa injection is used to reduce amyloid beta plaque, a protein found in the brain of people with Alzheimer's disease (a brain disease that slowly destroys the memory and ability to think, learn, communicate and handle daily activities). It is used to treat people with mild cognitive impairment (MCI) or mild dementia. Aducanumab-avwa injection is in a class of medications called monoclonal antibodies. It works by blocking the formation of amyloid beta in the brain.

How should this medicine be used?

Aducanumab-avwa injection comes as a solution (liquid) to be given into a vein by a doctor or nurse in a hospital or clinic. It is usually given over an hour once every 4 weeks.

Your doctor may need to interrupt your treatment or stop your treatment depending on your response to the medication and any side effects that you experience. Be sure to tell your doctor how you are feeling during your treatment.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before receiving aducanumab-avwa injection,

  • tell your doctor and pharmacist if you are allergic to aducanumab-avwa, any other medications, or any of the ingredients in aducanumab-avwa injection. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had any medical conditions.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while receiving aducanumab-avwa injection, call your doctor.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

If you miss an appointment to receive aducanumab-avwa injection, you should call your healthcare provider as soon as possible. Aducanumab-avwa injection doses should be given at least 21 days apart.

What side effects can this medication cause?

Aducanumab-avwa injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • diarrhea
  • falls

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

  • headache, confusion, dizziness, vision changes, or nausea
  • swelling of the face, lips, mouth, or tongue
  • hives

Aducanumab-avwa injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

In case of emergency/overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests such as magnetic resonance imaging (MRI; a medical test that uses powerful magnets to take pictures of the inside of the body) scans before and during treatment to check your body's response to aducanumab-avwa.

Ask your pharmacist any questions you have about aducanumab-avwa.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names

  • Aduhelm®
Last Revised - 07/15/2021