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pronounced as (fen il ef' rin)

Why is this medication prescribed?

Phenylephrine is used to relieve nasal discomfort caused by colds, allergies, and hay fever. It is also used to relieve sinus congestion and pressure. Phenylephrine will relieve symptoms but will not treat the cause of the symptoms or speed recovery. Phenylephrine is in a class of medications called nasal decongestants. It works by reducing swelling of the blood vessels in the nasal passages.

How should this medicine be used?

Phenylephrine comes as a tablet, a liquid, or a dissolving strip to take by mouth. It is usually taken every 4 hours as needed. Follow the directions on your prescription label or the package label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take phenylephrine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor or directed on the label.

Phenylephrine comes alone and in combination with other medications. Ask your doctor or pharmacist for advice on which product is best for your symptoms. Check nonprescription cough and cold product labels carefully before using two or more products at the same time. These products may contain the same active ingredient(s) and taking them together could cause you to receive an overdose. This is especially important if you will be giving cough and cold medications to a child.

Nonprescription cough and cold combination products, including products that contain phenylephrine, can cause serious side effects or death in young children. Do not give these products to children younger than 4 years of age. If you give these products to children 4 to 11 years of age, use caution and follow the package directions carefully.

If you are giving phenylephrine or a combination product that contains phenylephrine to a child, read the package label carefully to be sure that it is the right product for a child of that age. Do not give phenylephrine products that are made for adults to children.

Before you give a phenylephrine product to a child, check the package label to find out how much medication the child should receive. Give the dose that matches the child's age on the chart. Ask the child's doctor if you don't know how much medication to give the child.

If you are taking the liquid, do not use a household spoon to measure your dose. Use the measuring spoon or cup that came with the medication or use a spoon made especially for measuring medication.

If your symptoms do not get better within 7 days or if you have a fever, stop taking phenylephrine and call your doctor.

If you are taking the dissolving strips, place one strip on your tongue and allow it to dissolve.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking phenylephrine,

  • tell your doctor and pharmacist if you are allergic to phenylephrine, any other medications, or any of the ingredients in phenylephrine preparations.
  • do not take phenylephrine if you are taking a monoamine oxidase (MAO) inhibitor, such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), or if you have stopped taking one of these medications within the past 2 weeks.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
  • tell your doctor if you have or have ever had high blood pressure, diabetes, trouble urinating because of an enlarged prostate gland, or thyroid or heart disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking phenylephrine, call your doctor.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking phenylephrine.
  • if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent damage to your brain that can cause severe intellectual disability), you should know that some phenylephrine products may be sweetened with aspartame, a source of phenylalanine.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

This medication is usually taken as needed. If your doctor has told you to take phenylephrine regularly, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Phenylephrine may cause side effects. Some side effects can be serious. If you experience any of these symptoms, stop using phenylephrine and call your doctor:

  • nervousness
  • dizziness
  • sleeplessness

Phenylephrine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( for more information if you do not have access to a take-back program.

In case of emergency/overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

What other information should I know?

Ask your pharmacist any questions you have about phenylephrine.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names

  • Children's Sudafed PE Nasal Decongestant®
  • Lusonal®§
  • PediaCare Children's Decongestant®
  • Sudafed PE Congestion®
  • Suphedrin PE®

Brand names of combination products

  • A Tan 12x Suspension® (containing Phenylephrine, Pyrilamine)§
  • AccuHist® (containing Chlorpheniramine, Phenylephrine)
  • AccuHist PDX® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Actifed Cold and Allergy® (containing Chlorpheniramine, Phenylephrine)
  • Advil Congestion Relief® (containing Ibuprofen, Phenylephrine)
  • Aerohist Plus® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§
  • Aerokid® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)
  • Ah Chew® (containing Chlorpheniramine, Phenylephrine)§
  • Ah Chew Ultra® (containing Chlorpheniramine, Phenylephrine, Methscopolamine)§
  • Alahist DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Alahist LQ® (containing Diphenhydramine, Phenylephrine)
  • Albatussin NN® (containing Dextromethorphan, Phenylephrine, Potassium Guaiacolsulfonate, Pyrilamine)§
  • Aldex CT® (containing Diphenhydramine, Phenylephrine)
  • Aldex D® (containing Phenylephrine, Pyrilamine)
  • Alka-Seltzer Plus Cold and Cough Formula® (containing Aspirin, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Alka-Seltzer Plus Day and Night Cold Formulas® (containing Aspirin, Dextromethorphan, Phenylephrine)
  • Alka-Seltzer Plus Day Non-Drowsy Cold Formula® (containing Acetaminophen, Dextromethorphan, Phenylephrine)
  • Alka-Seltzer Plus Fast Powder Packs® (containing Acetaminophen, Chlorpheniramine, Phenylephrine)
  • Alka-Seltzer Plus Flu Formula® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Alka-Seltzer Plus Night Cold Formula® (containing Aspirin, Dextromethorphan, Doxylamine, Phenylephrine)
  • Alka-Seltzer Plus Sinus Formula® (containing Aspirin, Phenylephrine)
  • Alka-Seltzer Plus Sparkling Original Cold Formula® (containing Aspirin, Chlorpheniramine, Phenylephrine)
  • Allerest PE® (containing Chlorpheniramine, Phenylephrine)
  • Allergy DN PE® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§
  • AlleRx® (containing Chlorpheniramine, Phenylephrine)§
  • Amerituss AD® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Aquatab C® (containing Carbetapentane, Dextromethorphan, Guaifenesin, Phenylephrine)§
  • Aridex® (containing Carbetapentane, Carbinoxamine, Phenylephrine)
  • B Vex D® (containing Brompheniramine, Phenylephrine)§
  • Balacall DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Baltussin HC® (containing Chlorpheniramine, Hydrocodone, Phenylephrine)
  • Benadryl-D Allergy Plus Sinus® (containing Diphenhydramine, Phenylephrine)
  • Betatan® (containing Brompheniramine, Carbetapentane, Phenylephrine)§
  • Biotuss® (containing Dextromethorphan, Guaifenesin, Phenylephrine)§
  • BPM PE DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)§
  • Bromaphedrine D® (containing Brompheniramine, Phenylephrine)§
  • Bromhist PDX® (containing Brompheniramine, Dextromethorphan, Guaifenesin, Phenylephrine)§
  • Bromtuss DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)§
  • Broncopectol® (containing Chlorpheniramine, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Bronkids® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§
  • Brontuss DX® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Brontuss SF® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Brotapp PE-DM Cough and Cold® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Brovex D® (containing Brompheniramine, Phenylephrine)§
  • Brovex PEB® (containing Brompheniramine, Phenylephrine)
  • Brovex PEB DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • C Phen® (containing Chlorpheniramine, Phenylephrine)§
  • C Phen DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§
  • Cardec DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Centergy® (containing Chlorpheniramine, Phenylephrine)§
  • Centergy DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§
  • Centussin DHC® (containing Brompheniramine, Dihydrocodeine, Phenylephrine)§
  • Ceron® (containing Chlorpheniramine, Phenylephrine)
  • Ceron DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§
  • Cerose DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Children's Dimetapp Cold and Allergy® (containing Brompheniramine, Phenylephrine)
  • Children's Dimetapp Cold and Cough® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Children's Dimetapp Multisymptom Cold and Flu® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Children's Dimetapp Nighttime Cold and Congestion® (containing Diphenhydramine, Phenylephrine)
  • Children's Mucinex Multi-Symptom Cold® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Children's Mucinex Stuffy Nose and Cold® (containing Guaifenesin, Phenylephrine)
  • Children's Robitussin Cough and Cold CF® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Children's Sudafed PE Cold and Cough® (containing Dextromethorphan, Phenylephrine)
  • Chlordex GP® (containing Chlorpheniramine, Dextromethorphan, Guaifenesin, Phenylephrine)§
  • Codal-DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)
  • Codimal DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)
  • Comtrex Cold and Cough Day/Night® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Comtrex Cold and Cough Non-Drowsy® (containing Acetaminophen, Dextromethorphan, Phenylephrine)
  • Contac Cold and Flu® (containing Acetaminophen, Phenylephrine)
  • Corfen DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Coryza DM® (containing Dexchlorpheniramine, Dextromethorphan, Phenylephrine, Pyrilamine)§
  • Dallergy Drops® (containing Chlorpheniramine, Phenylephrine)
  • Dallergy PE® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§
  • Decon E® (containing Guaifenesin, Phenylephrine)§
  • Decon G® (containing Brompheniramine, Guaifenesin, Phenylephrine)§
  • Deconex® (containing Guaifenesin, Phenylephrine)
  • Dehistine® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§
  • Despec® (containing Guaifenesin, Phenylephrine)
  • Despec NR® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Donatuss DC® (containing Dihydrocodeine, Guaifenesin, Phenylephrine)§
  • Donatussin® (containing Guaifenesin, Phenylephrine)
  • Donatussin DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Donatussin MAX® (containing Carbinoxamine, Hydrocodone, Phenylephrine)
  • Dristan Cold Multi-Symptom Formula® (containing Acetaminophen, Chlorpheniramine, Phenylephrine)
  • Dryphen® (containing Acetaminophen, Chlorpheniramine, Phenylephrine)
  • Duravent-DPB® (containing Brompheniramine, Dextromethorphan, Phenylephrine)§
  • Dynatuss EX® (containing Dextromethorphan, Guaifenesin, Phenylephrine)§
  • EndaCof-DH® (containing Brompheniramine, Dihydrocodeine, Phenylephrine)
  • EndaCof-Plus® (containing Dexchlorpheniramine, Hydrocodone, Phenylephrine)
  • Endacon DM® (containing Dextromethorphan, Guaifenesin, Phenylephrine)§
  • Endal CD® (containing Chlorpheniramine, Codeine, Phenylephrine)
  • Endal HD® (containing Diphenhydramine, Phenylephrine)§
  • Entex LA® (containing Guaifenesin, Phenylephrine)§
  • Entex LQ® (containing Guaifenesin, Phenylephrine)
  • Excedrin Sinus Headache® (containing Acetaminophen, Phenylephrine)
  • Execof® (containing Dextromethorphan, Guaifenesin, Phenylephrine)§
  • Extendryl® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§
  • Genetuss 2® (containing Dextromethorphan, Guaifenesin, Phenylephrine)§
  • Gentex LQ® (containing Carbetapentane, Guaifenesin, Phenylephrine)§
  • Giltuss® (containing Dextromethorphan, Guaifenesin, Phenylephrine)§
  • Guiatex PE® (containing Guaifenesin, Phenylephrine)§
  • Histadec® (containing Chlorpheniramine, Phenylephrine)
  • Histinex HC® (containing Chlorpheniramine, Hydrocodone, Phenylephrine)
  • Hycomine Compound® (containing Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine)
  • J-Max® (containing Guaifenesin, Phenylephrine)
  • J-Tan D PD® (containing Brompheniramine, Phenylephrine)§
  • Lartus® (containing Dextromethorphan, Guaifenesin, Phelyephrine)§
  • Levall® (containing Carbetapentane, Guaifenesin, Phenylephrine)§
  • Liquibid D-R® (containing Guaifenesin, Phenylephrine)
  • Liquibid PD-R® (containing Guaifenesin, Phenylephrine)
  • Lohist-DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)§
  • LoHist-PEB® (containing Brompheniramine, Phenylephrine)
  • LoHist-PEB-DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Lortuss HC® (containing Hydrocodone, Phenylephrine)
  • Lusair® (containing Guaifenesin, Phenylephrine)
  • Lusonex® (containing Guaifenesin, Phenylephrine)§
  • Maxiphen® (containing Guaifenesin, Phenylephrine)§
  • Maxiphen ADT® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§
  • Mintuss DR® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§
  • Montephen® (containing Guaifenesin, Phenylephrine)§
  • MyHist DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)§
  • Naldex® (containing Dexchlorpheniramine, Phenylephrine)§
  • Nariz® (containing Guaifenesin, Phenylephrine)
  • Nasohist® (containing Chlorpheniramine, Phenylephrine)
  • Nasohist DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Neo DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§
  • NoHist® (containing Chlorpheniramine, Phenylephrine)§
  • NoHist-DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • NoHist-LQ® (containing Chlorpheniramine, Phenylephrine)
  • Norel DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§
  • Norel SR® (containing Acetaminophen, Chlorpheniramine, Phenylephrine, Phenyltoloxamine)§
  • Notuss-PE® (containing Codeine, Phenylephrine)
  • Novahistine® (containing Chlorpheniramine, Phenylephrine)
  • Omnihist II LA® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§
  • Oratuss® (containing Carbetapentane, Guaifenesin, Phenylephrine)§
  • PediaCare Children's Allergy and Cold® (containing Diphenhydramine, Phenylephrine)
  • PediaCare Children's Fever Reducer Plus Flu® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • PediaCare Children's Fever Reducer Plus Multi-Symptom Cold® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • PediaCare Children's Multi-Symptom Cold® (containing Dextromethorphan, Phenylephrine)
  • Phenabid® (containing Chlorpheniramine, Phenylephrine)§
  • Phencarb GG® (containing Carbetapentane, Guaifenesin, Phenylephrine)§
  • Phenergan VC® (containing Phenylephrine, Promethazine)
  • Poly Hist DHC® (containing Dihydrocodeine, Phenylephrine, Pyrilamine)§
  • Poly Hist DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)§
  • Poly Hist PD® (containing Chlorpheniramine, Phenylephrine, Pyrilamine)§
  • Polytan D® (containing Dexbrompheniramine, Phenylephrine)§
  • Polytan DM® (containing Dexbrompheniramine, Dextromethorphan, Phenylephrine, Pyrilamine)§
  • Poly-Tussin AC® (containing Brompheniramine, Codeine, Phenylephrine)
  • Poly-Tussin DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Poly-Tussin EX® (containing Dihydrocodeine, Guaifenesin, Phenylephrine)§
  • Prolex PD® (containing Guaifenesin, Phenylephrine)§
  • Prometh VC® (containing Phenylephrine, Promethazine)
  • Promethazine VC® (containing Phenylephrine, Promethazine)
  • Protid® (containing Acetaminophen, Chlorpheniramine, Phenylephrine)
  • Pyrlex PD® (containing Phenylephrine, Pyrilamine)§
  • Quartuss® (containing Chlorpheniramine, Dextromethorphan, Guaifenesin, Phenylephrine)§
  • Quartuss DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§
  • Quintex® (containing Guaifenesin, Phenylephrine)§
  • Re Allergy AM/PM® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§
  • Re Drylex® (containing Dexchlorpheniramine, Methscopolamine, Phenylephrine)§
  • Redur PCM® (containing Chlorpheniramine, Phenylephrine)§
  • Relcof PE® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§
  • RemeHist DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)§
  • RemeTussin DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§
  • Rescon® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§
  • Respa PE® (containing Guaifenesin, Phenylephrine)§
  • RespaHist II® (containing Brompheniramine, Phenylephrine)§
  • Resperal® (containing Dexchlorpheniramine, Dextromethorphan, Phenylephrine, Pyrilamine)
  • Rhinabid® (containing Brompheniramine, Phenylephrine)§
  • RhinaHist® (containing Dexchlorpheniramine, Phenylephrine)
  • Rinate® (containing Chlorpheniramine, Phenylephrine)
  • Robitussin Cough and Cold CF® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Robitussin Night Time Cough and Cold® (containing Diphenhydramine, Phenylephrine)
  • Robitussin Night Time Cough, Cold, and Flu® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Rondex® (containing Chlorpheniramine, Phenylephrine)
  • R-Tanna® (containing Chlorpheniramine, Phenylephrine)§
  • Ryna® (containing Phenylephrine, Pyrilamine)§
  • Rynatan® (containing Chlorpheniramine, Phenylephrine)§
  • Rynatuss® (containing Carbetapentane, Chlorpheniramine, Ephedrine, Phenylephrine)§
  • Ry-Tuss® (containing Carbetapentane, Chlorpheniramine, Ephedrine, Phenylephrine)§
  • ScopoHist® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§
  • Seradex® (containing Brompheniramine, Phenylephrine)§
  • Sildec PE DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§
  • Sine-Off Cough/Cold® (containing Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Sine-Off Non-Drowsy® (containing Acetaminophen, Phenylephrine)
  • Sine-Off Severe Cold® (containing Acetaminophen, Guaifenesin, Phenylephrine)
  • Sine-Off Sinus/Cold® (containing Acetaminophen, Chlorpheniramine, Phenylephrine)
  • Sinutuss DM® (containing Dextromethorphan, Guaifenesin, Phenylephrine)§
  • Sinuvent PE® (containing Guaifenesin, Phenylephrine)§
  • Sitrex® (containing Guaifenesin, Phenylephrine)§
  • Sonahist® (containing Chlorpheniramine, Phenylephrine)§
  • Sonahist DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§
  • Statuss DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§
  • Sudafed PE Cold/Cough® (containing Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Sudafed PE Day/Night Cold® (containing Acetaminophen, Dextromethorphan, Diphenhydramine, Guaifenesin, Phenylephrine)
  • Sudafed PE Day/Night Congestion® (containing Diphenhydramine, Phenylephrine)
  • Sudafed PE Non-Drying Sinus® (containing Guaifenesin, Phenylephrine)
  • Sudafed PE Pressure/Pain® (containing Acetaminophen, Phenylephrine)
  • Sudafed PE Severe Cold® (containing Acetaminophen, Diphenhydramine, Phenylephrine)
  • Sudafed PE Sinus/Allergy® (containing Chlorpheniramine, Phenylephrine)
  • Sudafed PE Triple Action® (containing Acetaminophen, Guaifenesin, Phenylephrine)
  • Sympak PDX® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§
  • Tanabid® (containing Brompheniramine, Phenylephrine)§
  • Tannate® (containing Carbetapentane, Phenylephrine, Pyrilamine)§
  • Theraflu Cold and Cough® (containing Dextromethorphan, Pheniramine, Phenylephrine)
  • Theraflu Cold and Sore Throat® (containing Acetaminophen, Pheniramine, Phenylephrine)
  • Theraflu Daytime Severe Cold and Cough® (containing Acetaminophen, Dextromethorphan, Phenylephrine)
  • Theraflu Flu and Sore Throat® (containing Acetaminophen, Pheniramine, Phenylephrine)
  • Theraflu Nighttime Severe Cold and Cough® (containing Acetaminophen, Diphenhydramine, Phenylephrine)
  • Theraflu Sinus and Cold® (containing Acetaminophen, Pheniramine, Phenylephrine)
  • Trexbrom® (containing Brompheniramine, Carbetapentane, Phenylephrine)§
  • Triall® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§
  • Triaminic Chest and Nasal Congestion® (containing Guaifenesin, Phenylephrine)
  • Triaminic Cold and Allergy® (containing Chlorpheniramine, Phenylephrine)
  • Triaminic Day Time Cold and Cough® (containing Dextromethorphan, Phenylephrine)
  • Triaminic Night Time Cold and Cough® (containing Diphenhydramine, Phenylephrine)
  • Triplex DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)§
  • Trital DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§
  • Tritan® (containing Chlorpheniramine, Phenylephrine, Pyrilamine)§
  • Trituss® (containing Dextromethorphan, Guaifenesin, Phenylephrine)§
  • Tusdec DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)§
  • Tussafed EX® (containing Dextromethorphan, Guaifenesin, Phenylephrine)§
  • Tussbid® (containing Guaifenesin, Phenylephrine)§
  • Tussi 12D® (containing Carbetapentane, Phenylephrine, Pyrilamine)§
  • Tussi Pres® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Tussidex® (containing Dextromethorphan, Guaifenesin, Phenylephrine)§
  • Tussin CF® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Tylenol Allergy Multi-Symptom® (containing Acetaminophen, Chlorpheniramine, Phenylephrine)
  • Tylenol Allergy Multi-Symptom Nighttime® (containing Acetaminophen, Diphenhydramine, Phenylephrine)
  • Tylenol Cold and Flu Severe® (containing Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Tylenol Cold Multi-Symptom Nighttime® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Tylenol Cold Multi-Symptom Severe® (containing Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Tylenol Sinus Congestion and Pain Daytime® (containing Acetaminophen, Phenylephrine)
  • Tylenol Sinus Congestion and Pain Nighttime® (containing Acetaminophen, Chlorpheniramine, Phenylephrine)
  • Tylenol Sinus Congestion and Pain Severe® (containing Acetaminophen, Guaifenesin, Phenylephrine)
  • V Tann® (containing Phenylephrine, Pyrilamine)§
  • Vanacof CD® (containing Dexchlorpheniramine, Phenylephrine)§
  • Vazobid® (containing Brompheniramine, Phenylephrine)§
  • Vazotan® (containing Brompheniramine, Carbetapentane, Phenylephrine)
  • V-Cof® (containing Brompheniramine, Carbetapentane, Phenylephrine)§
  • V-Hist® (containing Brompheniramine, Phenylephrine)§
  • Vicks DayQuil Cold and Flu Relief® (containing Acetaminophen, Dextromethorphan, Phenylephrine)
  • Vicks DayQuil Cold and Flu Symptom Relief Plus Vitamin C® (containing Acetaminophen, Dextromethorphan, Phenylephrine)
  • Vicks DayQuil Sinex Daytime Sinus Relief® (containing Acetaminophen, Phenylephrine)
  • Vicks Formula 44 Custom Care Congestion® (containing Dextromethorphan, Phenylephrine)
  • Vicks NyQuil Sinex Nighttime Sinus Relief® (containing Acetaminophen, Doxylamine, Phenylephrine)
  • Vicks VapoSyrup Severe Congestion® (containing Guaifenesin, Phenylephrine)
  • Viratan DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)§
  • Viravan DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)§
  • Viravan T® (containing Phenylephrine, Pyrilamine)§
  • Visonex® (containing Guaifenesin, Phenylephrine)§
  • Wellbid D® (containing Guaifenesin, Phenylephrine)§
  • Y-Cof DMX® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Z-Dex® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Zotex® (containing Dextromethorphan, Guaifenesin, Phenylephrine)§

This branded product is no longer on the market. Generic alternatives may be available.

§ These products are not currently approved by the FDA for safety, effectiveness, and quality. Federal law generally requires that prescription drugs in the U.S. be shown to be both safe and effective prior to marketing. Please see the FDA website for more information on unapproved drugs ( and the approval process (

Last Revised - 01/15/2022