What is acute flaccid myelitis (AFM)?
Acute flaccid myelitis (AFM) is a neurologic disease. It is rare, but serious. It affects an area of the spinal cord called gray matter. This can cause the muscles and reflexes in the body to become weak.
Because of these symptoms, some people call AFM a "polio-like" illness. But since 2014, people with AFM have been tested, and they did not have poliovirus.
What causes acute flaccid myelitis (AFM)?
Researchers think that viruses, including enteroviruses, likely play a role in causing AFM. Most people with AFM had a mild respiratory illness or fever (like you would get from a viral infection) before they got AFM.
Who is at risk for acute flaccid myelitis (AFM)?
Anyone can get AFM, but most cases (more than 90%) have been in young children.
What are the symptoms of acute flaccid myelitis (AFM)?
Most people with AFM will suddenly have:
- Arm or leg weakness
- A loss of muscle tone and reflexes
Some people also have other symptoms, including:
- Facial drooping/weakness
- Trouble moving the eyes
- Drooping eyelids
- Trouble swallowing
- Slurred speech
- Pain in the arms, legs, back, or neck
Sometimes AFM can weaken the muscles that you need for breathing. This can lead to respiratory failure, which is very serious. If you get respiratory failure, you may need to use a ventilator (breathing machine) to help you breathe.
If you or your child develops any of these symptoms, you should get medical care right away.
How is acute flaccid myelitis (AFM) diagnosed?
AFM causes many of the same symptoms as other neurologic diseases, such as transverse myelitis and Guillain-Barre syndrome. This can make it difficult to diagnose. The doctor may use many tools to make a diagnosis:
- A neurologic exam, including looking at where there is weakness, poor muscle tone, and decreased reflexes
- An MRI to look at the spinal cord and brain
- Lab tests on the cerebrospinal fluid (the fluid around the brain and spinal cord)
- Nerve conduction and electromyography (EMG) studies. These tests check nerve speed and the response of muscles to the messages from the nerves.
It is important that the tests are done as soon as possible after the symptoms start.
What are the treatments for acute flaccid myelitis (AFM)?
There is no specific treatment for AFM. A doctor who specializes in treating brain and spinal cord illnesses (neurologist) may recommend treatments for specific symptoms. For example, physical and/or occupational therapy may help with arm or leg weakness. Researchers do not know the long-term outcomes of people with AFM.
Can acute flaccid myelitis (AFM) be prevented?
Since viruses likley play a role in AFM, you should take steps to help prevent getting or spreading viral infections by:
- Washing hands often with soap and water
- Avoiding touching your face with unwashed hands
- Avoiding close contact with people who are sick
- Cleaning and disinfecting surfaces that you frequently touch, including toys
- Covering coughs and sneezes with a tissue or upper shirt sleeve, not hands
- Staying home when sick
Centers for Disease Control and Prevention
- Acute flaccid myelitis (Medical Encyclopedia) Also in Spanish
- Acute Flaccid Myelitis (Genetic and Rare Diseases Information Center) Also in Spanish
- Acute Flaccid Myelitis (Centers for Disease Control and Prevention)
- Acute Flaccid Myelitis in U.S. Children (Centers for Disease Control and Prevention)
- CDC Vital Signs: Acute Flaccid Myelitis (AFM) (Centers for Disease Control and Prevention)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Using the Acute Flaccid Paralysis Surveillance System to Identify Cases of...
- Article: Transcriptomic Profiling Reveals a Role for TREM-1 Activation in Enterovirus D68...
- Article: Surgical Innovations to Restore Function in Pediatric Peripheral Nerve Conditions.
- Acute Flaccid Myelitis -- see more articles